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34th Annual Scientific Meeting proceedings


Stream:   |   Session:
Date/Time: 30-11--0001 (00:00 - 00:00)   |   Location:
Perioperative analgesic effect of erector spinae block in pigs undergoing thoracic surgery: preliminary results
Nocera I1, Di Franco C2, Paganelli A1, Gabisonia K1, Modu M1, Carlucci L1, Briganti A3
1Institute of Health Science, Sant'Anna School Of Advanced Study, Pisa, Italy, 2Institute of Clinical Physiology, CNR San Cataldo Research Area, Pisa, Italy, 3Department of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, Pisa, Italy.

Objectives:

The erector spinae block (ESB) has been proven effective in controlling pain in thoracic surgery and chest trauma in both human and veterinary patients. This study aimed to evaluate the perioperative analgesic effect of the ESB in pigs undergoing lateral thoracotomy.

Methods:

For this blind randomized study, 18 pigs undergoing iatrogenic myocardial infarction were included. They were randomly divided into 2 groups: group Ropi, received, monolateral ropivacaine 0.5% 0.3 mL/kg (at the 6th thoracic vertebra with a caudocranial in-plane ultrasound-guided injection); group NaCl, received the ESB with saline solution in equal volume. Systemic blood pressure, end-tidal CO2, and end-tidal sevoflurane were recorded during anaesthesia heart rate. Pain was recorded 24 and 48 hours post-surgery, according to the UNESP-Botucatu pig pain scale. One-way ANOVA with a Tukey post hoc was used to compare the measurements for each time point within each group, while a student t-test or a Mann-Whitney was used to compare the 2 groups. Significance was set at p<0.05. The study was approved by the Italian Ministry of Health (n°0622).

Results:

During the procedure, heart rate and end-tidal sevoflurane values were significantly higher in group NaCl compared to group Ropi (p<0.05). Group Ropi showed a significantly lower pain score 48 hours post-surgery, 1 (0-3), compared to group NaCl, 3.5 (2-9) (p= 0.005), and within the same group Ropi between 24 2(1-8) and 48 (p = 0.004).

Conclusions:

Including ESB with ropivacaine 0.5% improved the quality of perioperative analgesia in pigs undergoing thoracic surgery.

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