Use of Subcutaneous Ureteral Bypass in three dogs affected by oncological disease.
Collivignarelli F, Giardina C, Dolce G, Bianchi A, Paolini A, Maggiolini U, Di Filippo L, Tamburro R
University of Teramo, Department of Veterinary Medicine, località piano d’Accio, 64100 Teramo Italy, Teramo, Italy.
Objectives:
This study aims to evaluate the surgical outcomes, complications, and prognostic factors in three dogs affected by oncological diseases undergoing Subcutaneous Ureteral Bypass (SUB) implantation.
Methods:
Inclusion criteria were dogs with malignant ureteral obstructions treated by SUB application.
All patients underwent the same protocol: all clinical and laboratory data (including blood chemistry, blood type, and CT scan results) was recorded and x-ray monitoring was conducted.
Results:
The observed causes of obstruction were abdominal sarcoma surrounding the ureter (n=1),
compression from metastatic lymph nodes in the context of prostatic carcinoma (n=1), and
failure of ureteral reimplantation after prostatectomy performed for infiltrating prostatic
carcinoma in the trigone region (n=1).
All patients were treated with the SUB device; the nephrostomy catheter was placed unilaterally in two dogs and bilaterally in one patient.
Preoperative levels of creatinine and BUN, initially elevated
(median creatinine 4.7 mg/dl; BUN 80 mg/dl), showed improvements upon follow-up.
Major complications included catheter dislodgement from the renal pelvis with uroabdomen.
Minor complications included incontinence and urinary tract infections (n=2).
The presence of metastases in cases of malignant obstruction was identified as a negative prognostic factor.
The intraoperative mortality was 0%, while postoperative (120 days following operation) mortality was 66%.
Conclusions:
The application of SUB represents a valid therapeutic option, whether curative or palliative. It also serves as a life-saving treatment in patients already subjected to total cystectomy. Patient selection and clear communication with the owner are crucial for proper surgical outcome.